A Novel Approach for Oral Delivery of Insulin via Desmodium gangeticum Aqueous Root Extract
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چکیده
منابع مشابه
A Novel Approach for Oral Delivery of Insulin via Desmodium gangeticum Aqueous Root Extract
Many challenges are associated with the oral delivery of insulin, relating to the physical and chemical stability of the hormone, and its absorption and metabolism in the human body. The present study aims to demonstrate the oral delivery of insulin in both normal and steptozotocin (STZ)-induced diabetic rats with the help of the aqueous extract of Desmodium gangeticum (DG) root. Human insulin ...
متن کاملAdministration of aqueous extract of Desmodium gangeticum (L) root protects rat heart against ischemic reperfusion injury induced oxidative stress.
Myocardial reperfusion is believed to be associated with free radical injury. The present study evaluates the effect of aqueous extract of D. gangeticum (DG) on lipid peroxides and antioxidants in ischemic reperfused (IR) Wistar albino male rats. Significant elevation in lipid peroxide products (thiobarbituric acid reactive substances) and decreased activity of antioxidant enzymes (superoxide d...
متن کاملCardiotonic and Anti Ischemic Reperfusion Injury Effect of Desmodium Gangeticum Root Methanol Extract
Objectives: Anti ischemic reperfusion effect of crude methanol extract of Desmodium gangeticum root had been reported earlier but how is modulating its cardiotonic effect to render cardio-protection is largely unknown. Methods: The inotropic effect of methanol extract of Desmodium gangeticum root was investigated on isolated frog heart and further analyzed the physiological and biochemical effe...
متن کاملAntiamnesic effects of Desmodium gangeticum in mice.
Dementia is a mental disorder characterized by loss of intellectual ability sufficiently severe enough to interfere with one's occupational or social activities. Desmodium gangeticum commonly known as Salparni, is widely used in ayurveda for the treatment of neurological disorders. The present work was designed to assess the potential of aqueous extract of D. gangeticum (DG) as a nootropic agen...
متن کاملAntioxidant effects of ethyl acetate extract of Desmodium gangeticum root on myocardial ischemia reperfusion injury in rat hearts
BACKGROUND This study aims to evaluate the antioxidant potential of the ethyl acetate extract of Desmodium gangeticum root for cardioprotection from ischemia reperfusion-induced oxidative stress. METHODS The in vitro antioxidant potential of the extract was in terms of hydroxyl radical scavenging activity, lipid peroxide scavenging activity, nitric oxide scavenging activity and diphenylpicryl...
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ژورنال
عنوان ژورنال: Journal of Young Pharmacists
سال: 2010
ISSN: 0975-1483
DOI: 10.4103/0975-1483.63158